Products
OGDH antibody
- Product Name
- OGDH antibody
- Catalogue No.
- FNab05976
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
- Alternative Names
- AKGDH antibody
- UniProt ID
- Q02218
- Observed MW
- 116 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Validated Images
mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab05976( OGDH Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse brain using FNab05976(OGDH antibody) at dilution of 1:100
- Background
- This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
