Products
NKRF antibody
- Product Name
- NKRF antibody
- Catalogue No.
- FNab05747
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- NFKB repressing factor
- Alternative Names
- ITBA4 antibody, NRF antibody
- UniProt ID
- O15226
- Observed MW
- 100 kDa
Application
- Tested Applications
- ELISA, WB, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:2000
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab05747(NKRF antibody) at dilution of 1:1000
IP Result of anti-NKRF (IP:FNab05747, 3ug; Detection:FNab05747 1:1000) with A549 cells lysate 1000ug.
- Background
- Interacts with a specific negative regulatory element(NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription.
