Products

NF-L antibody

Synonyms:68 kDa neurofilament protein antibody, CMT1F antibody, CMT2E antibody, FLJ53642 antibody, NEFL antibody, NF L antibody, NF68 antibody, NFL antibody
Catalogue No.:FNab05710Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
NF-L antibody
Catalogue No.
FNab05710
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
neurofilament, light polypeptide
Alternative Names
68 kDa neurofilament protein antibody, CMT1F antibody, CMT2E antibody, FLJ53642 antibody, NEFL antibody, NF L antibody, NF68 antibody, NFL antibody
UniProt ID
P07196
Observed MW
68 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:100 - 1:500; IF: 1:50 - 1:200
Validated Images
Various lysates were subjected to SDS PAGE followed by western blot with FNab05710(NEFL antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain tissue slide using FNab05710( NEFL Antibody) at dilution of 1:200
Background
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.