Products
NEDD4 antibody
- Product Name
- NEDD4 antibody
- Catalogue No.
- FNab05645
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- neural precursor cell expressed, developmentally down-regulated 4
- Alternative Names
- KIAA0093 antibody, NEDD4-1 antibody
- UniProt ID
- P46934
- Observed MW
- 120 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
C6 cells were subjected to SDS PAGE followed by western blot with FNab05645(NEDD4 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human gastric using FNab05645( NEDD4 Antibody) at dilution of 1:200
- Background
- This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.
