Products
MYOT antibody
- Product Name
- MYOT antibody
- Catalogue No.
- FNab05521
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- myotilin
- Alternative Names
- TTID antibody
- UniProt ID
- Q9UBF9
- Observed MW
- 55 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100
Validated Images
mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab05521(MYOT antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse heart using FNab05521(MYOT antibody) at dilution of 1:100
- Background
- This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
