mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab05471( MYH10 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain tissue slide using FNab05471( MYH10 Antibody) at dilution of 1:100
Background
This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-10 (MYO10). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene have been associated with May-Hegglin anomaly and developmental defects in brain and heart. Multiple transcript variants encoding different isoforms have been found for this gene.