anti- Myelin basic protein antibody

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Product Information
Product name

anti- Myelin basic protein antibody

Alternative name

Myelin basic protein Antibody

Catalogue No.

FNab05465

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Description

Myelin basic protein antibody: Rabbit Polyclonal antibody to Myelin basic protein

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

Background

The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.

Immunogen Information
Immunogen

myelin basic protein

Synonyms

MBP, Myelin A1 protein, Myelin basic protein

Calculated MW

34 kDa

Application
Specificity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC, IF

Recommended dilution

WB: 1:500 – 1:2000; IHC: 1:50 – 1:200; IF: 1:50 – 1:200

Uniprot information
Gene Name

Myelin basic protein

Uniprot ID

P02686

Images

anti- Myelin basic protein antibody 1

Immunohistochemistry of paraffin-embedded rat kidney tissue slide using FNab05465 (MBP Antibody) at dilution of 1:200


anti- Myelin basic protein antibody 1

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab05465 (MBP Antibody) at dilution of 1:1000

Current product's manual: Manual

Protocol may be updated. Please feel free to contact Finetest Team to acquire the latest version.

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Hotline

027-87384275
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