Products

MYD88 antibody

Synonyms:MYD88 antibody, MYD88D antibody
Catalogue No.:FNab09835Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
MYD88 antibody
Catalogue No.
FNab09835
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
myeloid differentiation primary response gene
Alternative Names
MYD88 antibody, MYD88D antibody
UniProt ID
Q99836
Observed MW
33 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500 - 1:2000
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09835(MYD88 antibody) at dilution of 1:1000
Background
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.