Products
MVP/LRP antibody
- Product Name
- MVP/LRP antibody
- Catalogue No.
- FNab05449
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- major vault protein
- Alternative Names
- LRP antibody, major vault protein antibody, MVP antibody, VAULT1 antibody
- UniProt ID
- Q14764
- Observed MW
- 100 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Validated Images
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab05449(MVP antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab05449( MVP Antibody) at dilution of 1:200
Immunofluorescence analysis of U2OS cells using FNab05449( MVP Antibody) at dilution of 1:100. Blue: DAPI for nuclear staining.
- Background
- This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.
