HeLa cells were subjected to SDS PAGE followed by western blot with FNab05429(MUC16,CA125 antibody) at dilution of 1:500
IP Result of anti-MUC16,CA125 (IP:FNab05429, 4ug; Detection:FNab05429 1:600) with HeLa cells lysate 1200ug.
Immunohistochemistry of paraffin-embedded human ovary tumor tissue slide using FNab05429(MUC16,CA125 Antibody) at dilution of 1:200
Background
MUC16, also named as CA125, is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. It is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller “subunits” being described by some investigators. The antibody recognizes the C-term of MUC16.