MUC16,CA125 antibody

Synonyms:CA 125 antibody, CA125 antibody, FLJ14303 antibody, MUC 16 antibody, MUC16 antibody, Mucin 16 antibody
Catalogue No.:FNab05429Reactivity:Human
Host:RabbitTested Application:ELISA, WB, IP,IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
MUC16,CA125 antibody
Catalogue No.
FNab05429
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
mucin 16, cell surface associated
Alternative Names
CA 125 antibody, CA125 antibody, FLJ14303 antibody, MUC 16 antibody, MUC16 antibody, Mucin 16 antibody
UniProt ID
Q8WXI7
Observed MW
90-100 kDa
Application
Tested Applications
ELISA, WB, IP,IHC
Recommended dilution
WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:50-1:500
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab05429(MUC16,CA125 antibody) at dilution of 1:500
IP Result of anti-MUC16,CA125 (IP:FNab05429, 4ug; Detection:FNab05429 1:600) with HeLa cells lysate 1200ug.
Immunohistochemistry of paraffin-embedded human ovary tumor tissue slide using FNab05429(MUC16,CA125 Antibody) at dilution of 1:200
Background
MUC16, also named as CA125, is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. It is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller “subunits” being described by some investigators. The antibody recognizes the C-term of MUC16.