MCF7 cells were subjected to SDS PAGE followed by western blot with FNab05391(MTAP antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse liver using FNab05391(MTAP antibody) at dilution of 1:100
Background
This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.