Products
MRPL1 antibody
- Product Name
- MRPL1 antibody
- Catalogue No.
- FNab05312
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- mitochondrial ribosomal protein L1
- Alternative Names
- BM022 antibody
- UniProt ID
- Q9BYD6
- Observed MW
- 37 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:20 - 1:200
Validated Images
human liver tissue were subjected to SDS PAGE followed by western blot with FNab05312(MRPL1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach tissue slide using FNab05312(MRPL1 Antibody) at dilution of 1:50
- Background
- Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family.
