Products
MRAP2 antibody
- Product Name
- MRAP2 antibody
- Catalogue No.
- FNab05304
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- melanocortin 2 receptor accessory protein 2
- Alternative Names
- C6orf117 antibody
- UniProt ID
- Q96G30
Application
- Tested Applications
- ELISA, IHC
- Recommended dilution
- IHC: 1:20-1:200
Validated Images
Immunohistochemistry of paraffin-embedded human brain using FNab05304(MRAP2 antibody) at dilution of 1:50
- Background
- Modulator of melanocortin receptor 4(MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP(By similarity). May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin(ACTH) to MC2R. May also regulate activity of other melanocortin receptors(MC1R, MC3R and MC5R); however, additional evidences are required in vivo.
