Products
MMP14 antibody
- Product Name
- MMP14 antibody
- Catalogue No.
- FNab05236
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- matrix metallopeptidase 14 (membrane-inserted)
- Alternative Names
- MMP-14 antibody
- UniProt ID
- P50281
- Observed MW
- 65 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab05236(MMP14 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer using FNab05236(MMP14 Antibody) at dilution of 1:100
- Background
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
