Products
MMP1 antibody
- Product Name
- MMP1 antibody
- Catalogue No.
- FNab05233
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- matrix metallopeptidase 1 (interstitial collagenase)
- Alternative Names
- CLG antibody, CLGN antibody, Fibroblast collagenase antibody, Interstitial collagenase antibody, Matrix metalloproteinase 1 antibody, MMP 1 antibody, MMP1 antibody
- UniProt ID
- P03956
- Observed MW
- 54 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
A549 cells were subjected to SDS PAGE followed by western blot with FNab05233(MMP1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using FNab05233( MMP1 Antibody) at dilution of 1:200
- Background
- This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
