LRPPRC antibody

Synonyms:LRP130 antibody
Catalogue No.:FNab04850Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
LRPPRC antibody
Catalogue No.
FNab04850
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
leucine-rich PPR-motif containing
Alternative Names
LRP130 antibody
UniProt ID
P42704
Observed MW
140 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:1000 - 1:2000; IHC: 1:100 - 1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab04850(LRPPRC antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver using FNab04850(LRPPRC antibody) at dilution of 1:100
Background
This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome.