Products

LOXL1 antibody

Synonyms:LOL antibody, LOXL antibody, LOXL1 antibody, Lysyl oxidase homolog 1 antibody, lysyl oxidase like 1 antibody, Lysyl oxidase like protein 1 antibody
Catalogue No.:FNab09975Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
LOXL1 antibody
Catalogue No.
FNab09975
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
lysyl oxidase-like 1
Alternative Names
LOL antibody, LOXL antibody, LOXL1 antibody, Lysyl oxidase homolog 1 antibody, lysyl oxidase like 1 antibody, Lysyl oxidase like protein 1 antibody
UniProt ID
Q08397
Observed MW
70kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500 - 1:2000
Validated Images
A549 cells were subjected to SDS PAGE followed by western blot with FNab09975(LOXL1 Antibody) at dilution of 1:1000
Background
This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome.