Products
LIMS1 antibody
- Product Name
- LIMS1 antibody
- Catalogue No.
- FNab04782
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- LIM and senescent cell antigen-like domains 1
- Alternative Names
- PINCH antibody, PINCH1 antibody
- UniProt ID
- P48059
- Observed MW
- 40 kDa
Application
- Tested Applications
- ELISA, WB, IF, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Validated Images
human kidney tissue were subjected to SDS PAGE followed by western blot with FNab04782(LIMS1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human oesophagus cancer using FNab04782(LIMS1 antibody) at dilution of 1:50
- Background
- The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
