mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab04512(KDM4A antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse lung using FNab04512(KDM4A antibody) at dilution of 1:100
Background
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.