HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab04451( JPH1 Antibody) at dilution of 1:2000
Background
Junctophilins contribute to the formation of junctional membrane complexes(JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH1 contributes to the construction of the skeletal muscle triad by linking the t-tubule(transverse-tubule) and SR(sarcoplasmic reticulum) membranes.