mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab04442(JMJD6 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse brain using FNab04442(JMJD6 antibody) at dilution of 1:100
Background
This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.