Products

IL1 beta antibody

Synonyms:IL1 beta antibody, Catabolin antibody, IL 1 antibody, IL 1 beta antibody, IL1 BETA antibody, IL1B antibody, IL1beta antibody, IL1F2 antibody, IL-1β antibody, Interleukin 1 beta antibody, interleukin 1 antibody, beta antibody
Catalogue No.:FNab04209Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IHC, WB
Clonality:polyclonalIsotype:IgG
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Product Name
IL1 beta antibody
Catalogue No.
FNab04209
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
interleukin 1, beta
Alternative Names
IL1 beta antibody, Catabolin antibody, IL 1 antibody, IL 1 beta antibody, IL1 BETA antibody, IL1B antibody, IL1beta antibody, IL1F2 antibody, IL-1β antibody, Interleukin 1 beta antibody, interleukin 1 antibody, beta antibody
UniProt ID
P01584
Observed MW
17,35-40 kDa
Application
Tested Applications
ELISA, IHC, WB
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
A549 cells were subjected to SDS PAGE followed by western blot with FNab04209( IL1B Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat lung using FNab04209(IL1B antibody) at dilution of 1:50
Background
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.