Products
IL-4 antibody
- Product Name
- IL-4 antibody
- Catalogue No.
- FNab09861
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- interleukin 4
- Alternative Names
- BCGF-1 antibody
- UniProt ID
- P05112
- Observed MW
- Refer to figures
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500 - 1:1000
Validated Images
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09861( IL-4 antibody) at dilution of 1:700
- Background
- The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
