K-562 cells were subjected to SDS PAGE followed by western blot with FNab04202(IKBKG antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human esophagus using FNab04202(IKBKG antibody) at dilution of 1:50
Background
This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.