Products

IkB beta antibody

Synonyms:I kappa B beta antibody, IkappaBbeta antibody, IkB B antibody, IkB beta antibody, IKBB antibody, NF kappa B inhibitor beta antibody, NF kappa BIB antibody, NFKBIB antibody, TR interacting protein 9 antibody, TRIP 9 antibody, TRIP9 antibody
Catalogue No.:FNab04199Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
IkB beta antibody
Catalogue No.
FNab04199
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
Alternative Names
I kappa B beta antibody, IkappaBbeta antibody, IkB B antibody, IkB beta antibody, IKBB antibody, NF kappa B inhibitor beta antibody, NF kappa BIB antibody, NFKBIB antibody, TR interacting protein 9 antibody, TRIP 9 antibody, TRIP9 antibody
UniProt ID
Q15653
Observed MW
40 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab04199(NFKBIB antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer using FNab04199(NFKBIB antibody) at dilution of 1:100
Immunofluorescence analysis of U2OS cells using FNab04199(NFKBIB antibody). Blue: DAPI for nuclear staining.
Background
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.