IGF2BP3 antibody

Synonyms:IMP3 antibody, KOC1 antibody, VICKZ3 antibody
Catalogue No.:FNab04173Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
IGF2BP3 antibody
Catalogue No.
FNab04173
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
insulin-like growth factor 2 mRNA binding protein 3
Alternative Names
IMP3 antibody, KOC1 antibody, VICKZ3 antibody
UniProt ID
O00425
Observed MW
72 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab04173(IGF2BP3 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver using FNab04173(IGF2BP3 antibody) at dilution of 1:100
Background
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.