Products
IDH1 antibody
- Product Name
- IDH1 antibody
- Catalogue No.
- FNab04119
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 1G10
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- isocitrate dehydrogenase 1(NADP+), soluble
- Alternative Names
- IDCD antibody, IDH antibody, IDH1 antibody, IDP antibody, IDPC antibody, NADP(+) specific ICDH antibody, Oxalosuccinate decarboxylase antibody, PICD antibody
- UniProt ID
- O75874
- Observed MW
- 46kd
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500
Validated Images
MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab04119(IDH1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human pancreas tissue slide using FNab04119(IDH1 Antibody) at dilution of 1:200
- Background
- IDH1, also named as PICD and IDP, belongs to the isocitrate and isopropylmalate dehydrogenases family. It is a common feature of a major subset of primary human brain cancers. It can form a homodimer(PMID:15173171).IDH1 mutation is always heterozygotic and IDH1 functions as a dimer, theoretically there will be 25% each wild type and mutant homo-dimers and 50% hetero-dimers present in the tumor cells(PMID:21079649 ).
