Products
HTR3A antibody
- Product Name
- HTR3A antibody
- Catalogue No.
- FNab04067
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- 5-hydroxytryptamine (serotonin) receptor 3A
- Alternative Names
- 5HT3R antibody, HTR3 antibody
- UniProt ID
- P46098
- Observed MW
- 55 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab04067(HTR3A antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain using FNab04067( HTR3A Antibody) at dilution of 1:50
- Background
- The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
