Products
HMGB1 antibody
- Product Name
- HMGB1 antibody
- Catalogue No.
- FNab03924
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- high-mobility group box 1
- Alternative Names
- DKFZp686A04236 antibody, high mobility group box 1 antibody, High mobility group protein 1 antibody, High mobility group protein B1 antibody, HMG 1 antibody, HMG1 antibody, HMG3 antibody, HMGB1 antibody, SBP 1 antibody
- UniProt ID
- P09429
- Observed MW
- 26 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab03924(HMGB1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab03924(HMGB1 antibody) at dilution of 1:100
Immunofluorescence analysis of HeLa cells using FNab03924 (HMGB1 antibody) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
- Background
- This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.
