DU 145 cells were subjected to SDS PAGE followed by western blot with FNab03867(HIP1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse brain using FNab03867(HIP1 Antibody) at dilution of 1:50
Background
The product of this gene is a membrane-associated protein that functions in clathrin-mediated endocytosis and protein trafficking within the cell. The encoded protein binds to the huntingtin protein in the brain; this interaction is lost in Huntington's disease. Alternative splicing results in multiple transcript variants.