HDAC6 antibody

Synonyms:HD6 antibody, HDAC6 antibody, histone deacetylase 6 antibody, JM21 antibody, KIAA0901 antibody
Catalogue No.:FNab03803Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
HDAC6 antibody
Catalogue No.
FNab03803
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
histone deacetylase 6
Alternative Names
HD6 antibody, HDAC6 antibody, histone deacetylase 6 antibody, JM21 antibody, KIAA0901 antibody
UniProt ID
Q9UBN7
Observed MW
170 kDa
Application
Tested Applications
ELISA, WB, IHC, IP
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP : 1:20 - 1:50
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab03803(HDAC6 antibody) at dilution of 1:1000
IP Result of anti-HDAC6 (IP:FNab03803, 5ug; Detection:FNab03803 1:1000) with K-562 cells lysate 11000ug.
Immunohistochemistry of paraffin-embedded human testis using FNab03803(HDAC6 antibody) at dilution of 1:50
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.