Products

HDAC4 antibody

Synonyms:KIAA0288 antibody
Catalogue No.:FNab03800Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
HDAC4 antibody
Catalogue No.
FNab03800
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
histone deacetylase 4
Alternative Names
KIAA0288 antibody
UniProt ID
P56524
Observed MW
130 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:1000; IHC: 1:50 - 1:100
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab03800(HDAC4 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab03800(HDAC4 antibody) at dilution of 1:100
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.