Products

HDAC3 antibody

Synonyms:HD3 antibody
Catalogue No.:FNab03798Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IHC, IP, WB, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
HDAC3 antibody
Catalogue No.
FNab03798
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
histone deacetylase 3
Alternative Names
HD3 antibody
UniProt ID
O15379
Observed MW
47 kDa
Application
Tested Applications
ELISA, IHC, IP, WB, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:200; IP: 1:50 - 1:200; ChIP: 1:20 - 1:100
Validated Images
HL-60 cells were subjected to SDS PAGE followed by western blot with FNab03798( HDAC3 Antibody) at dilution of 1:1000
IP Result of anti-HDAC3 (IP:FNab03798, 3ug; Detection:FNab03798 1:300) with A431 cells lysate 1200ug.
Immunohistochemistry of paraffin-embedded human esophagus using FNab03798(HDAC3 antibody) at dilution of 1:100
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.