Products
HDAC1 antibody
- Product Name
- HDAC1 antibody
- Catalogue No.
- FNab03792
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- histone deacetylase 1
- Alternative Names
- DKFZp686H12203 antibody, GON 10 antibody, HD1 antibody, HDAC1 antibody, histone deacetylase 1 antibody, RPD3 antibody, RPD3L1 antibody
- UniProt ID
- Q13547
- Observed MW
- 60 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:100 - 1:200; IF: 1:50 - 1:100
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab03792(HDAC1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human prostate cancer using FNab03792(HDAC1 antibody) at dilution of 1:100
Immunofluorescence analysis of A549 cells using FNab03792 (HDAC1 antibody). Blue: DAPI for nuclear staining.
- Background
- Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
