Products

HAX1 antibody

Synonyms:FLJ17042 antibody, FLJ18492 antibody, FLJ93803 antibody, HAX 1 antibody, HAX1 antibody, HCLS1 associated protein X 1 antibody, HCLSBP1 antibody, HS1 associating protein X 1 antibody, HS1 binding protein 1 antibody, HS1BP1 antibody, HSP1BP 1 antibody, SCN3 antibody
Catalogue No.:FNab03765Reativity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
HAX1 antibody
Catalogue No.
FNab03765
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
HCLS1 associated protein X-1
Alternative Names
FLJ17042 antibody, FLJ18492 antibody, FLJ93803 antibody, HAX 1 antibody, HAX1 antibody, HCLS1 associated protein X 1 antibody, HCLSBP1 antibody, HS1 associating protein X 1 antibody, HS1 binding protein 1 antibody, HS1BP1 antibody, HSP1BP 1 antibody, SCN3 antibody
UniProt ID
O00165
Observed MW
36 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab03765( HAX1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse heart using FNab03765(HAX1 antibody) at dilution of 1:50
Immunofluorescence analysis of A549 cells using FNab03765(HAX1 antibody). Blue: DAPI for nuclear staining.
Background
The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.