Products
HAT1 antibody
- Product Name
- HAT1 antibody
- Catalogue No.
- FNab03761
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- histone acetyltransferase 1
- Alternative Names
- KAT1 antibody
- UniProt ID
- O14929
- Observed MW
- 50 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, IP
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200; ChIP: 1:50 - 1:200
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab03761(HAT1 antibody) at dilution of 1:1000
IP Result of anti-HAT1 (IP:FNab03761, 4ug; Detection:FNab03761 1:500) with HepG2 cells lysate 3200ug.
Immunohistochemistry of paraffin-embedded mouse osteosarcoma using FNab03761(HAT1 antibody) at dilution of 1:50
- Background
- The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.
