Jurkat cells were subjected to SDS PAGE followed by western blot with FNab03699(GSTP1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer using FNab03699(GSTP1 antibody) at dilution of 1:200
Immunofluorescent analysis of HepG2 cells using FNab03699 (GSTP1 Antibody) at dilution of 1:50 and Rhodamine-labeled goat anti-rabbit IgG (red).
Background
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.