mouse ovary tissue were subjected to SDS PAGE followed by western blot with FNab03673(GSK3B antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat kidney using FNab03673( GSK3B Antibody) at dilution of 1:100
Background
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.