Products

GRB2 antibody

Synonyms:ASH antibody
Catalogue No.:FNab03642Reativity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IF, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
GRB2 antibody
Catalogue No.
FNab03642
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
growth factor receptor-bound protein 2
Alternative Names
ASH antibody
UniProt ID
P62993
Observed MW
33 kDa
Application
Tested Applications
ELISA, WB, IF, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100
Validated Images
SW480 cells were subjected to SDS PAGE followed by western blot with FNab03642(GRB2 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse kidney using FNab03642(GRB2 antibody) at dilution of 1:100
Background
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.