GPT antibody

Synonyms:AAT1 antibody, GPT1 antibody
Catalogue No.:FNab03619Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
GPT antibody
Catalogue No.
FNab03619
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
glutamic-pyruvate transaminase (alanine aminotransferase)
Alternative Names
AAT1 antibody, GPT1 antibody
UniProt ID
P24298
Observed MW
50 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:200 - 1:1000; IHC: 1:50 - 1:100
Validated Images
mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab03619(GPT antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab03619(GPT antibody) at dilution of 1:50
Background
This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.