Products

GPI antibody

Synonyms:AMF antibody, Autocrine motility factor antibody, g6pi antibody, Glucose 6 phosphate isomerase antibody, glucose phosphate isomerase antibody, GNPI antibody, GPI antibody, Neuroleukin antibody, NLK antibody, PGI antibody, PHI antibody, Phosphoglucose isomerase antibody, Phosphohexose isomerase antibody, SA 36 antibody, Sperm antigen 36 antibody
Catalogue No.:FNab03582Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
GPI antibody
Catalogue No.
FNab03582
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
glucose phosphate isomerase
Alternative Names
AMF antibody, Autocrine motility factor antibody, g6pi antibody, Glucose 6 phosphate isomerase antibody, glucose phosphate isomerase antibody, GNPI antibody, GPI antibody, Neuroleukin antibody, NLK antibody, PGI antibody, PHI antibody, Phosphoglucose isomerase antibody, Phosphohexose isomerase antibody, SA 36 antibody, Sperm antigen 36 antibody
UniProt ID
P06744
Observed MW
56 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
PC-3 cells were subjected to SDS PAGE followed by western blot with FNab03582(GPI antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat kidney using FNab03582( GPI Antibody) at dilution of 1:200
Immunofluorescence analysis of U2OS cells using FNab03582( GPI Antibody) Blue: DAPI for nuclear staining.
Background
This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants.