mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab03372(GBF1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human esophagus using FNab03372(GBF1 antibody) at dilution of 1:100
Background
This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene.