GARS antibody

Synonyms:AP 4 A synthetase antibody, CMT2D antibody, DSMAV antibody, GARS antibody, Glycine tRNA ligase antibody, glycyl tRNA synthetase antibody, GlyRS antibody, HMN5 antibody, SMAD1 antibody
Catalogue No.:FNab03347Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
GARS antibody
Catalogue No.
FNab03347
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
glycyl-tRNA synthetase
Alternative Names
AP 4 A synthetase antibody, CMT2D antibody, DSMAV antibody, GARS antibody, Glycine tRNA ligase antibody, glycyl tRNA synthetase antibody, GlyRS antibody, HMN5 antibody, SMAD1 antibody
UniProt ID
P41250
Observed MW
70-83 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
human brain tissue were subjected to SDS PAGE followed by western blot with FNab03347(GARS antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded mouse brain using FNab03347(GARS antibody) at dilution of 1:50
Background
This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.