Products
GAD2 antibody
- Product Name
- GAD2 antibody
- Catalogue No.
- FNab03291
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- Alternative Names
- GAD65 antibody
- UniProt ID
- Q05329
- Observed MW
- 70 kDa
Application
- Tested Applications
- ELISA, WB, IF, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab03291(GAD2 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain using FNab03291(GAD2 antibody) at dilution of 1:100
- Background
- This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
