A549 cells were subjected to SDS PAGE followed by western blot with FNab03186(FOSL2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human esophagus using FNab03186(FOSL2 antibody) at dilution of 1:100
Background
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.