Products
FLNB antibody
- Product Name
- FLNB antibody
- Catalogue No.
- FNab03161
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- filamin B, beta (actin binding protein 278)
- Alternative Names
- FLN1L antibody, FLN3 antibody, TABP antibody, TAP antibody
- UniProt ID
- O75369
- Observed MW
- 298 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:1000; IHC: 1:20 - 1:50
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab03161(FLNB antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver injury using FNab03161(FLNB antibody) at dilution of 1:100
- Background
- This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
