FHIT antibody

Synonyms:AP3Aase antibody, FRA3B antibody
Catalogue No.:FNab09817Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
FHIT antibody
Catalogue No.
FNab09817
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
FHIT
Alternative Names
AP3Aase antibody, FRA3B antibody
UniProt ID
P49789
Observed MW
35 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab09817 at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse heart tissue slide using FNab09817( FHIT antibody) at dilution of 1:200
Background
This gene, a member of the histidine triad gene family, encodes a diadenosine 5', 5'''-P1, P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.