Products

FBL antibody

Synonyms:FIB1 antibody, FLRN antibody
Catalogue No.:FNab03027Reativity:Human, Mouse
Host:RabbitTested Application:ELISA, IF, IHC, WB, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
FBL antibody
Catalogue No.
FNab03027
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
fibrillarin
Alternative Names
FIB1 antibody, FLRN antibody
UniProt ID
P22087
Observed MW
37 kDa
Application
Tested Applications
ELISA, IF, IHC, WB, IP
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200; IP: 1:20 - 1:50
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab03027(FBL antibody) at dilution of 1:1000
IP Result of anti-FBL (IP:FNab03027, 4ug; Detection:FNab03027 1:500) with A375 cells lysate 3600ug.
Immunohistochemistry of paraffin-embedded mouse liver using FNab03027(FBL antibody) at dilution of 1:100
Background
This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.