Products

FASN antibody

Synonyms:FAS antibody
Catalogue No.:FNab03019Reativity:Human, Mouse
Host:RabbitTested Application:ELISA, IF, IHC, WB
Clonality:polyclonalIsotype:IgG
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Product Name
FASN antibody
Catalogue No.
FNab03019
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
fatty acid synthase
Alternative Names
FAS antibody
UniProt ID
P49327
Observed MW
280 kDa
Application
Tested Applications
ELISA, IF, IHC, WB
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab03019(FASN antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer using FNab03019(FASN antibody) at dilution of 1:100
Background
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.