mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab02930(FABP3 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human ovary using FNab02930(FABP3 antibody) at dilution of 1:100
Immunofluorescence analysis of U2OS cells using FNab02930(FABP3 antibody). Blue: DAPI for nuclear staining.
Background
The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants.